Simvastatin FDA Link Generic

A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.

Also Known As:

Zocor; MK-733; Synvinolin; MK 733; MK733

Pharmalogical Action Categories:

Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypolipidemic Agents

Organic Chemicals: 140
- Hydrocarbons: 1726
  - Cyclic Hydrocarbons: 96
    - Aromatic Hydrocarbons: 295
      - Polycyclic Aromatic Hydrocarbons: 2081
        Naphthalenes: 18
        Lovastatin: 1557
        Simvastatin: 4980
Polycyclic Compounds: 7
- Polycyclic Aromatic Hydrocarbons: 2081
  - Naphthalenes: 18
    - Lovastatin: 1557
      - Simvastatin: 4980

R J Esper Selected Research

R J Esper Research Topics

Disease

Drug/Important Bio-Agent (IBA)